Recombinant adenovirus containing hyper-interleukin-6 and hepatocyte growth factor ameliorates acute-on-chronic liver failure in rats

Figure 7 Expression of mRNA levels of hyper-IL-6 or HGF as detected by representative reverse transcription-polymerase chain reaction. A: Hyper-IL-6 mRNA; B: HGF mRNA. The Y axis represents the relative mRNA expression of Hyper-IL-6 or HGF compared to that of the house-keeping gene β-actin for all types of treated liver. ^bP < 0.01 vs Ad-GFP treated, ^cP < 0.01 vs Ad-HIL-6 treated, ^dP < 0.01 vs Ad-HGF treated, ^eP > 0.05 vs Ad-HGF treated and ^fP > 0.05 vs Ad-HIL-6 treated. The results are expressed as the mean ± SD, n = 6. Control: Normal liver; Model: ACLF liver; Ad-GFP: pDC315-3FLAG-sv40-EGFP; Ad-HIL-6: pDC315-3FLAG-sv40-Hyper-IL-6-EGFP; Ad-HGF: pDC315-3FLAG-sv40-HGF-EGFP; and Ad-HGF-HIL-6: pDC315-3FLAG-sv40-HGF-IRES-Hyper-IL-6-EGFP.