Combined mesenchymal stem cell transplantation and interleukin-1 receptor antagonism after partial hepatectomy

Figure 9 Hepatic cell proliferation. Expression of Ki67 protein was determined by immunohistochemistry in A: Normal, sham-operated control; B: After hepatectomy; C: With MSC transplantation; D: Treatment with IL-1Ra; and E: Combined MSC transplantation and IL-1Ra (magnification × 100; scale bar = 20 μm); F: Percentage of Ki67-stained hepatocytes per total number of hepatocytes was used as calculate the Ki67 index. ^aP < 0.05, ^bP < 0.01 vs hepatectomy. IL-1Ra: Interleukin-1 receptor antagonist; MSC: Mesenchymal stem cell transplantation.