Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines

Figure 5 Rate of apoptosis in ATP7B mutant cell lines after copper exposure. Cells were exposed to 100 μmol/L Cu for 24 h. Induction of apoptosis was determined by Annexin-V staining followed by flow cytometry analysis. Data is represented as mean ± SE of at least three independent experiments. ^aP < 0.05 vs KO cells expressing wild type ATP7B.