Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease

Figure 2 Alcoholic hepatitis induces macrophage polarization. A: Serum bilirubin was measured in serum samples at week 15; B: Liver mRNA levels of macrophage markers, F4/80, CD68; C: Liver mRNA levels of M1 macrophage markers, IL-1β, iNOS; D: Liver mRNA levels of M2 macrophage markers, Arg1, CD163, IL-10, and CD206. In graphs, values are given as mean ± SD, Dunnett’s multiple comparison were used to compare the means of multiple groups; ^aP < 0.05. NS: Not significant; DEN: Diethyl nitrosamine; IL: Interleukin; iNOS: Inducible nitric oxide synthase.