Lymphocyte-to-monocyte ratio predicts survival after radiofrequency ablation for colorectal liver metastases

Table 3 Cox univariate/multivariate regression for time to recurrence

Variables	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age (reference ≤ 65 yr)	1.01 (0.57-1.59)	0.61
Gender (reference F)	1.29 (0.63-1.91)	0.52
Monocyte ratio (reference ≤ 5%)	1.23 (0.47-2.11)	0.45
NLR (reference ≤ 2.1)	1.49 (0.88-2.89)	0.04	1.28 (0.21- 4.75)	0.26
LMR (reference ≤ 3.96)	0.62 (0.40-0.95)	0.02	0.41 (0.25-0.89)	0.01
CEA (reference ≤ 38 ng/mL)	1.69 (1.04-4.21)	0.02	1.38 (1.12-3.48)	0.22
Number of nodules (reference 1)	1.41 (1.11-3.64)	0.05	1.53 (1.23-3.49)	0.10
Max Diameter (reference ≤ 30 mm)	2.29 (1.58-5.2)	< 0.001	3.59 (1.86-6.31)	0.003
Primary tumor (reference colon)	1.12 (0.52-1.64)	0.48
Timing (reference synchronous)	1.21 (0.89-1.75)	0.41
ECOG PS (reference 0)	1.01 (0.72-1.34)	0.87

NLR: Neutrophil-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; CEA: Carcinoembryonic antigen; ECOG: Eastern Cooperative Oncology Group; PS: Performance status.