Lymphocyte-to-monocyte ratio predicts survival after radiofrequency ablation for colorectal liver metastases

Table 2 Cox univariate/multivariate regression for overall survival

Variables	Univariate analysis		Multivariate analysis
	Hazard ratio (95%CI)	P value	Hazard ratio (95%CI)	P value
Age (reference ≤ 65 yr)	1.16 (0.68-1.95)	0.39
Gender (reference F)	1.41 (0.58-3.1)	0.14
Monocyte ratio (reference ≤ 5%)	1.38 (0.46-2.78)	0.16
NLR (reference ≤ 2.1)	1.62 (0.87-3.64)	0.03	1.48 (0.22- 2.79)	0.14
LMR (reference ≤ 3.96)	0.53 (0.34-0.85)	0.007	0.49 (0.29-0.96)	0.02
CEA (reference ≤ 34 ng/mL)	1.83 (1.24-4.07)	0.01	1.38 (1.03-2.54)	0.32
Number of nodules (reference 1)	1.69 (1.13-4.22)	0.02	1.27 (2.02-6.63)	0.48
Max diameter (reference ≤ 30 mm)	2.1 (1.59-5.1)	0.002	2.49 (1.45-5.46)	0.001
Primary tumor (reference colon)	1.18 (0.46-1.43)	0.34
Timing (reference synchronous)	1.29 (0.77-1.84)	0.21
ECOG PS (reference 0)	1.54 (0.94-2.75)	0.09

NLR: Neutrophil-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; CEA: Carcinoembryonic antigen; ECOG: Eastern Cooperative Oncology Group; PS: Performance status.