Copyright
©The Author(s) 2016.
World J Gastroenterol. Apr 28, 2016; 22(16): 4168-4182
Published online Apr 28, 2016. doi: 10.3748/wjg.v22.i16.4168
Published online Apr 28, 2016. doi: 10.3748/wjg.v22.i16.4168
HCC (n = 192) | Cirrhotic (n = 96) | Non-cirrhotic (n = 96) | Control (n = 95) | P value | |
Age, mean ± SD (range) | 56.7 ± 7.7a (29-80) | 54.01 ± 8.3b (27-66) | 40.54 ± 8.82c (22-61) | 33.37 ± 11d (19-62) | < 0.001 |
Gender | |||||
Male | 152a (79) | 67a (70) | 78a (81) | 21b (22) | < 0.001 |
Female | 40 a (21) | 29a (30) | 18a (19) | 74b (78) | |
Smoker | |||||
Yes | 75a (39) | 26ab (27) | 20b (21) | 3c (3) | < 0.001 |
No | 117a (61) | 70ab (73) | 76b (79) | 92c (97) | |
DM | |||||
Yes | 43a (22) | 22a (23) | 8b (8) | 0c (0) | < 0.001 |
No | 149a (78) | 74a (77) | 88b (92) | 95c (100) | |
HCV Ab | |||||
Present | 168a (88) | 90a (94) | 96b (100) | 0c | < 0.001 |
Absent | 24a (12) | 6a (6) | 0b (0) | 95c (100) | |
HBs Ag | |||||
Present | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0.57 |
Absent | 191 (100) | 96 (100) | 96 (100) | 95 (100) | |
Ascites | |||||
Yes | 86a (45) | 75b (78) | 0c (0) | 0c (0) | < 0.001 |
No | 106a (55) | 21b (22) | 96c (100) | 95c (100) | |
Child score | |||||
A | 69a (36) | 12b (12) | < 0.001 | ||
B | 69a (36) | 27a (28) | |||
C | 49a (28) | 57b (60) | |||
ALT, | |||||
mean | 64.79 ± 52.737 | 63.6 ± 42.54 | 63.41 ± 44.22 | 21.84 ± 5.04 | < 0.001 |
(range) | (5-395) | (6-290) | (10-223) | (11-33) | |
median | 51a | 60a | 54a | 22b | |
AST, | |||||
mean | 94.39 ± 105.61 | 53.91 ± 31.72 | 47.53 ± 29.04 | 26.68 ± 5.07 | < 0.001 |
(range) | (16-1155) | (16-176) | (8-167) | ( 15-37) | |
median | 77a | 46.5b | 39.5b | 27c | |
T-Bil, | |||||
mean | 2.4 ± 2.63 | 3.25 ± 2.51 | 0.88 ± 0.49 | 0.79 ± 0.16 | < 0.001 |
(range) | (0.3-25.8) | (0.2-19.7) | (0.3-5) | (0.5-1.1) | |
median | 1.7a | 2.86b | 0.84c | 0.8c | |
Albumin, | |||||
mean | 3.02 ± 0.63 | 2.55 ± 0.51 | 4.28 ± 0.4 | 4.45 ± 0.34 | < 0.001 |
(range) | (1.8-4.8) | (1.7-4.3) | (3.2-5.4) | (3.8-5.2) | |
median | 3.1a | 2.5b | 4.2c | 4.5d | |
AFP, | |||||
mean | 3933.25 ± 16142 | 35.21 ± 40.1 | 18.19 ± 29.62 | < 0.001 | |
(range) | (1.5-114170) | (1.7-190) | (0.65-112) | 0 | |
median | 152a | 17.95b | 4.6c | 0d |
- Citation: Zekri ARN, Youssef ASED, Bakr YM, Gabr RM, Ahmed OS, Elberry MH, Mayla AM, Abouelhoda M, Bahnassy AA. Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model. World J Gastroenterol 2016; 22(16): 4168-4182
- URL: https://www.wjgnet.com/1007-9327/full/v22/i16/4168.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i16.4168