Total pancreatectomy with islet cell transplantation vs intrathecal narcotic pump infusion for pain control in chronic pancreatitis

doi:10.3748/wjg.v22.i16.4160

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Apr 28, 2016 (publication date) through Nov 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2016; 22(16): 4160-4167
Published online Apr 28, 2016. doi: 10.3748/wjg.v22.i16.4160

Table 4 Summary of outcomes among patients with intrathecal narcotic pump and those with total pancreatectomy and islet cell transplantation

	ITNP	TP + ICT	Comparison
Reversibility of the procedure	Yes	No	Different
Success rate for pain control	77%	80%	Similar
Residual narcotic dose usage (mg equivalent of oral morphine sulfate)	Mean = 158 mg/d	Mean = 104 mg/d	Similar
	Median = 8 mg/d	Median = 40 mg/d	Similar
Percentage of patients with poor pain control	16.7%	11.1%	Similar
Percentage of patients with new insulin dependent diabetes	0%	Approximately 85%	Different
Procedure related death	0%	10%	Different

ITNP: Intrathecal narcotic pump; TP: Total pancreatectomy; ICT: Islet cell transplantation.

Citation: Mokadem M, Noureddine L, Howard T, McHenry L, Sherman S, Fogel EL, Watkins JL, Lehman GA. Total pancreatectomy with islet cell transplantation vs intrathecal narcotic pump infusion for pain control in chronic pancreatitis. World J Gastroenterol 2016; 22(16): 4160-4167
URL: https://www.wjgnet.com/1007-9327/full/v22/i16/4160.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i16.4160