Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-κB signaling in colorectal cancer cells

Figure 8 Nuclear factor-κB signaling pathway mediated the integrin-linked kinase-induced epithelial-mesenchymal transition occurrence. A: Western blot detection of p-IκBa, IγBa, and NF-κB expression; B: Statistical analysis, in which the difference between the vector group and vector-ILK group was statistically significant; C: After treatment with siRNA, E-cadherin expression was detected in cells; D: Statistical analysis: the difference between the vector-ILK cell line in the siRNAp65 treated group and control siRNA group was statistically significant. This experiment was repeated three times. ILK: Integrin-linked kinase; NF-κB: Nuclear factor-κB; siRNA, small interfering RNA.