Integrin αvβ6 and matrix metalloproteinase 9 correlate with survival in gastric cancer

Figure 1 Comparison of immunohistochemical staining of αvβ6 and MMP-9 in the same gastric cancer specimen evaluated with formalin-fixed, paraffin-embedded tissue (streptavidin-peroxidase method; original magnification × 400). Positive αvβ6 expression was detected predominantly in the cell membrane, and matrix metalloproteinase 9 (MMP-9) mainly exhibited a cytoplasmic immunostaining in tumor cells. A: Positive αvβ6 expression; B: Negative αvβ6 expression; C: Positive MMP-9 expression; D: Negative MMP-9 expression.