Copyright
©The Author(s) 2016.
World J Gastroenterol. Apr 14, 2016; 22(14): 3860-3868
Published online Apr 14, 2016. doi: 10.3748/wjg.v22.i14.3860
Published online Apr 14, 2016. doi: 10.3748/wjg.v22.i14.3860
Health economic sub-group | Entire POCER study cohort | P value | |
n = 60 | n = 174 | ||
n (male) | 24 (40) | 78 (45) | 0.516 |
Age > 40 yr | 24 (40) | 68 (39) | 0.900 |
Age, median | 37 | 36 | |
Age at diagnosis | |||
≤ 16 yr | 4 (7) | 19 (11) | 0.340 |
17-40 yr | 49 (81) | 134 (77) | 0.451 |
> 40 yr | 7 (12) | 21 (12) | 0.934 |
Duration of Crohn's disease ≥ 10 yr | 29 (48) | 60 (34) | 0.154 |
Disease location at surgery: | |||
Ileum only (L1) | 33 (55) | 95 (55) | 0.957 |
Colon only (L2) | 3 (5) | 11 (6) | 0.710 |
Ileum and colon (L3) | 21 (35) | 68 (39) | 0.575 |
Disease phenotype at surgery: | |||
B1 (Inflammatory) | 5 (8) | 17 (10) | 0.742 |
B2 (Stricture) | 18 (30) | 62 (36) | 0.428 |
B3 (Penetrating) | 37 (62) | 95 (55) | 0.341 |
Indication for surgery: | |||
Failure of drug therapy | 12 (20) | 38 (22) | 0.764 |
Obstruction | 14 (23) | 50 (29) | 0.418 |
Perforation | 34 (57) | 86 (49) | 0.333 |
Number of prior surgical resections | |||
0 | 47 (78) | 124 (71) | 0.287 |
1 | 9 (15) | 33 (19) | 0.490 |
2 | 1 (2) | 9 (5) | 0.247 |
3 or more | 3 (5) | 8 (5) | 0.899 |
Active smoker | 22 (37) | 54 (31) | 0.422 |
Immediate post-operative baseline drug therapy | |||
Metronidazole alone | 9 (15) | 29 (17) | 0.763 |
Thiopurine | 39 (65) | 101 (58) | 0.343 |
Adalimumab | 12 (20) | 44 (25) | 0.408 |
CDAI > 150 | 40 (67) | 113 (65) | 0.673 |
CDAI > 200 | 30 (50) | 90 (52) | 0.465 |
- Citation: Wright EK, Kamm MA, Dr Cruz P, Hamilton AL, Ritchie KJ, Bell SJ, Brown SJ, Connell WR, Desmond PV, Liew D. Cost-effectiveness of Crohn’s disease post-operative care. World J Gastroenterol 2016; 22(14): 3860-3868
- URL: https://www.wjgnet.com/1007-9327/full/v22/i14/3860.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i14.3860