Liver cancer stem cell markers: Progression and therapeutic implications

doi:10.3748/wjg.v22.i13.3547

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2016; 22(13): 3547-3557
Published online Apr 7, 2016. doi: 10.3748/wjg.v22.i13.3547

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Figure 2 Proposed hierarchy of liver cancer stem cells according to the current literature. Liver cancer stem cell markers have been defined that can give rise to ALDH⁺CD133⁺, EpCAM⁺CD90⁺, CD133⁺CD44⁺ and other early progenitor cells, each of which can subsequently divide into more differentiated progenitor cells. Rounded arrows show cells with self-renewal capacity that have the potential to serve as CSCs. Small arrows show the unproven potential for “de-differentiation”. CSCs: Cancer stem cells.

Citation: Sun JH, Luo Q, Liu LL, Song GB. Liver cancer stem cell markers: Progression and therapeutic implications. World J Gastroenterol 2016; 22(13): 3547-3557
URL: https://www.wjgnet.com/1007-9327/full/v22/i13/3547.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i13.3547