Deficiency of platelet-derived growth factor receptor-α-positive cells in Hirschsprung's disease colon

Figure 2 Western blot of platelet-derived growth factor receptor-α protein expression. A: Platelet-derived growth factor receptor-α (PDGFRα) protein expression was high in normal controls and markedly decreased in both ganglionic and aganglionic specimens. The loading control GAPDH was similarly expressed in normal controls, ganglionic and aganglionic specimens; B: Densitometry analysis showed the range of PDGFRα protein expression among the samples studied. ^aP values are significant vs normal control.