Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis

Table 3 Testing of anorectal motility and rectal visceral sensation in each group

	Normal	IBS-D	UC in remission
Initial sensory threshold (mL)	50.18 ± 4.19	23.91 ± 10.15a	20.10 ± 9.17b
Defecation threshold (mL)	69.15 ± 10.75	35.17 ± 12.71a	21.28 ± 10.32b
Pain threshold (mL)	105.90 ± 20.15	70.10 ± 11.25a	50.33 ± 12.30b
Maximum compliance (mL/mmHg)	4.95 ± 1.81	5.02 ± 1.75	4.98 ± 1.91
Resting pressure (mmHg)	62.15 ± 15.21	65.54 ± 13.15	63.27 ± 10.15
Relaxation pressure (mmHg)	105.15 ± 60.15	140.50 ± 55.50a	138.69 ± 52.82a
Relaxation pressure (mmHg)	43.18 ± 22.50	45.15 ± 20.65	46.10 ± 19.97

^aP < 0.05,

^bP < 0.01 vs normal. UC: Ulcerative colitis; IBS-D: Diarrhea-predominant irritable bowel syndrome.