Copyright
©The Author(s) 2016.
World J Gastroenterol. Mar 28, 2016; 22(12): 3418-3431
Published online Mar 28, 2016. doi: 10.3748/wjg.v22.i12.3418
Published online Mar 28, 2016. doi: 10.3748/wjg.v22.i12.3418
Table 1 Patient demographics and baseline disease characteristics
| n (%) | GT1b | GT1a | ||
| DCV + pegIFN/RBV (n = 268) | TVR + pegIFN/RBV (n = 134) | DCV + pegIFN/RBV (n = 134) | TVR + pegIFN/RBV (n = 66) | |
| Age (yr), median (range) | 46.0 (18-71) | 48.0 (19-69) | 49.0 (19-67) | 51.5 (28-69) |
| Male | 159 (59.3) | 72 (53.7) | 98 (73.1) | 47 (71.2) |
| Race | ||||
| White | 243 (90.7) | 129 (96.3) | 120 (89.6) | 63 (95.5) |
| Black/African American | 16 (6.0) | 3 (2.2) | 11 (8.2) | 2 (3.0) |
| Asian | 6 (2.2) | 2 (1.5) | 1 (0.7) | 0 |
| Other | 3 (1.1) | 0 | 2 (1.5) | 1 (1.5) |
| HCV-RNA log10 (IU/mL), mean (SD) | 6.23 (0.701) | 6.23 (0.577) | 6.30 (0.637) | 6.31 (0.636) |
| HCV-RNA ≥ 800000 IU/mL | 196 (73.1) | 97 (72.4) | 104 (77.6) | 51 (77.3) |
| IL28B genotype | ||||
| CC | 53 (19.8) | 27 (20.1) | 42 (31.3) | 20 (30.3) |
| CT | 161 (60.1) | 86 (64.2) | 73 (54.5) | 37 (56.1) |
| TT | 53 (19.8) | 21 (15.7) | 19 (14.2) | 9 (13.6) |
| Not reported | 1 (0.4) | 0 | 0 | 0 |
| Cirrhosis | ||||
| Present | 26 (9.7) | 15 (11.2) | 16 (11.9) | 9 (13.6) |
- Citation: Jacobson I, Zeuzem S, Flisiak R, Knysz B, Lueth S, Zarebska-Michaluk D, Janczewska E, Ferenci P, Diago M, Zignego AL, Safadi R, Baruch Y, Abdurakhmanov D, Shafran S, Thabut D, Bruck R, Gadano A, Thompson AJ, Kopit J, McPhee F, Michener T, Hughes EA, Yin PD, Noviello S. Daclatasvir vs telaprevir plus peginterferon alfa/ribavirin for hepatitis C virus genotype 1. World J Gastroenterol 2016; 22(12): 3418-3431
- URL: https://www.wjgnet.com/1007-9327/full/v22/i12/3418.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i12.3418