Donor preoperative oxygen delivery and post-extubation hypoxia impact donation after circulatory death hypoxic cholangiopathy

Table 6 Era 1 and era 2 risk comparisons

	Era 1	Era 2	P value
DCD liver transplants	17	27
Hypoxic cholangiopathy	29.4%	63.0%	0.030
Transplants per year	2.5	7.1	0.100
Hepatocellular carcinoma	23.5%	51.9%	0.060
Donor body mass index (kg/m2)	24.1 ± 3.1	26.7 ± 4.3	0.030
Donor hypoxia accrual time (min)	17.3 ± 5.0	22.7 ± 4.8	0.001
Donor extubation-to-asystole time (min)	9.3 ± 4.5	14.4 ± 4.7	0.001
Donor aystole-to-crossclamp time (min)	8.1 ± 2.7	8.3 ± 2.3	0.779
Donor ischemia time (min)	9.7 ± 5.6	13.9 ± 5.9	0.030
Donor hypoxemia time (min)	11.1 ± 6.7	16.0 ± 5.1	0.013
Donor hypoxia score	1.6 ± 0.9	2.7 ± 1.1	0.003
Donor hypoxia score > 2.0	28.6%	73.1%	0.006
Recipient cold ischemia time (min)	381 ± 139	461 ± 111	0.040
Recipient warm ischemia time (min)	31 ± 10	39 ± 15	0.030
Recipient total ischemia time (min)	411.8 ± 135	499.4 ± 119	0.030