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©The Author(s) 2016.
World J Gastroenterol. Mar 28, 2016; 22(12): 3372-3380
Published online Mar 28, 2016. doi: 10.3748/wjg.v22.i12.3372
Published online Mar 28, 2016. doi: 10.3748/wjg.v22.i12.3372
APE1 Asp148Glu/T-656G | ||||||||
Asp/T | Asp/G | Glu/T | Glu/G | |||||
Ca/Co (%)1 | OR (95%CI)2 | Ca/Co (%)1 | OR (95%CI)2 | Ca/Co (%)1 | OR (95%CI)2 | Ca/Co (%)1 | OR (95%CI)2 | |
All | 41.1/41.5 | 1.00 (ref) | 16.3/17.7 | 0.93 (0.75-1.15) | 14.5/13.4 | 1.09 (0.87-1.37) | 28.1/27.5 | 1.03 (0.86-1.24) |
Gender | ||||||||
Male | 42.5/40.0 | 1.00 (ref) | 16.0/16.8 | 0.87 (0.66-1.16) | 14.5/14.6 | 0.91 (0.67-1.22) | 27.1/29.7 | 0.84 (0.66-1.06) |
Female | 39.3/44.6 | 1.00 (ref) | 16.7/18.9 | 1.00 (0.73-1.36) | 14.5/11.8 | 1.39 (0.98-1.97) | 29.5/24.7 | 1.36 (1.03-1.78)a |
Age at diagnosis (yr) | ||||||||
≤ 60 | 42.1/42.7 | 1.00 (ref) | 17.1/17.2 | 1.01 (0.74-1.38) | 15.7/14.8 | 1.08 (0.77-1.50) | 25.0/25.3 | 1.00 (0.76-1.32) |
> 60 | 40.3/40.5 | 1.00 (ref) | 15.6/18.1 | 0.87 (0.65-1.15) | 13.5/12.3 | 1.10 (0.81-1.50) | 30.6/29.1 | 1.06 (0.84-1.34) |
Tumor site | ||||||||
Colon | 40.4/41.5 | 1.00 (ref) | 16.7/17.7 | 0.96 (0.74-1.25) | 15.5/13.4 | 1.20 (0.91-1.58) | 27.4/27.5 | 1.03 (0.82-1.28) |
Rectum | 41.7/41.5 | 1.00 (ref) | 16.0/17.7 | 0.90 (0.69-1.16) | 13.5/13.4 | 0.99 (0.75-1.31) | 28.8/27.5 | 1.04 (0.84-1.29) |
Stage | ||||||||
0, I, II | 41.1/41.5 | 1.00 (ref) | 15.8/17.7 | 0.90 (0.69-1.17) | 14.9/13.4 | 1.14 (0.86-1.51) | 28.2/27.5 | 1.02 (0.82-1.28) |
III, IV | 41.1/41.5 | 1.00 (ref) | 16.7/17.7 | 0.95 (0.74-1.23) | 14.1/13.4 | 1.06 (0.81-1.39) | 28.1/27.5 | 1.04 (0.84-1.29) |
- Citation: Lai CY, Hsieh LL, Tang R, Santella RM, Chang-Chieh CR, Yeh CC. Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan. World J Gastroenterol 2016; 22(12): 3372-3380
- URL: https://www.wjgnet.com/1007-9327/full/v22/i12/3372.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i12.3372