Lipids in liver transplant recipients

Table 3 Proposed targeted triglyceride serum concentrations in liver transplant recipients[42]

Triglyceride-targets and -limits
Triglyceride-targeted serum concentrations < 200 mg/dL
Triglycerides < 400 mg/dL with life-style intervention1: tolerable
Triglycerides < 500 mg/dL despite lipid-lowering medication before start of immunosuppression: no initiation of therapy with mTOR-inhibitors
Triglycerides > 500 mg/dL under mTOR-inhibitors: if despite therapy triglycerides < 500 mg/dL, change to different group of immunosuppressant (or reduce doses)

¹Life-style modification/ therapy (lipid-lowering medication): (1) weight loss; (2) increase physical activity; (3) optimize glucose-metabolism; and (4) lipid lowering agents. mTOR: Mammalian target of rapamycin.