Hepatitis B and D viruses replication interference: Influence of hepatitis B genotype

Table 3 Hepatitis B virus serological profile of patients

			Serum HBV-DNA			HBsAg
	Genotype1	Anti-HBe	Status2	Log10 (IU/mL) (range)	VC	Log10 (IU/mL) (range)	VC
Pat #1	Und	Positive	Negative	NA	NA	4.40 ± 0.13 (4.20-4.48)	0.03
Pat #2	A	Positive	Negative	NA	NA	4.60 ± 0.09 (4.56-4.66)	0.02
Pat #3	E	Positive	Positive	2.80 ± 0.29 (2.60-3.01)	0.10	4.46 ± 0.10 (4.39-4.53)	0.02
Pat #4	A	Positive	Positive	1.75 ± 1.20 (1.30-2.95)	0.69	3.53 ± 0.14 (3.44-3.63)	0.04
Pat #5	A	Positive	Positive	3.25 ± 1.30 (2.13-4.35)	0.40	4.87 ± 0.06 (4.86-4.93)	0.01
Pat #6	D	Positive	Fluctuating	2.32 ± 0.70 (1.00-3.42)	0.30	4.52 ± 0.27 (4.01-4.78)	0.06
Pat #7	E	Positive	Fluctuating	1.36 ± 0.45 (1.00-2.48)	0.33	3.94 ± 0.10 (3.80-4.12)	0.03
Pat #8	D	Positive	Fluctuating	1.65 ± 0.92 (1.00-2.30)	0.56	4.64 ± 0.07 (4.59-4.69)	0.02
Pat #9	A	Positive	Fluctuating	1.62 ± 0.88 (1.00-2.48)	0.54	4.17 ± 0.68 (3.68-4.64)	0.16
Pat #10	D	Positive	Positive	3.17 ± 0.56 (2.22-4.08)	0.18	3.99 ± 0.19 (3.64-4.13)	0.05
Pat #11	A	Positive	Negative	NA	NA	4.55 ± 0.07 (4.48-4.63)	0.02
Pat #12	D	Negative	Fluctuating	3.22 ± 1.40 (1.00-4.99)	0.43	4.45 ± 0.09 (4.30-4.58)	0.02
Pat #13	A	Positive	Negative	NA	NA	3.85 ± 0.17 (3.73-3.97)	0.04
Pat #14	D	Positive	Fluctuating	2.11 ± 0.73 (1.00-2.93)	0.35	3.75 ± 0.10 (3.68-3.82)	0.03
Pat #15	D	Positive	Positive	2.76 ± 0.95 (1.97-4.76)	0.34	3.55 ± 0.20 (3.20-3.73)	0.06
Pat #16	E	Positive	Positive	2.36 ± 0.10 (2.30-2.48)	0.04	4.28 ± 0.10 (4.21-4.35)	0.02

¹Genotyping results obtained by the combined use of LiPA and PCR/Sequencing techniques (see material and methods);

²Evolution of HBV-DNA during follow-up. Fluctuating is defined as a patient with alternating positive and negative samples. HBV: Hepatitis B virus; VC: Variation coefficient; NA: Not applicable; Und: Undetermined genotype because of HBV-DNA negativity.