Copyright
©The Author(s) 2016.
World J Gastroenterol. Mar 14, 2016; 22(10): 2981-2992
Published online Mar 14, 2016. doi: 10.3748/wjg.v22.i10.2981
Published online Mar 14, 2016. doi: 10.3748/wjg.v22.i10.2981
Variable | Number of persons | Univariate analysis | Multivariate analysis1 | |||
Non-adenoma | Adenoma | OR (95%CI) | P value | OR (95%CI) | P value | |
(n = 1523) | (n = 253) | |||||
Males | 1060 (69.6) | 211 (83.4) | 2.19 (1.55-3.11) | < 0.001 | 1.43 (0.89-2.28) | 0.136 |
Age (yr) | ||||||
45-49 | 386 (25.3) | 105 (41.5) | 1 | < 0.001 | 1 | |
40-44 | 504 (33.1) | 87 (34.4) | 0.64 (0.46-0.87) | 0.64 (0.46-0.88) | 0.006 | |
< 40 | 633 (41.6) | 61 (24.1) | 0.35 (0.25-0.50) | 0.39 (0.28-0.56) | < 0.001 | |
Body mass index (kg/m2) | ||||||
mean ± SD | 23.5 ± 3.2 | 24.4 ± 3.1 | ||||
18.5-24.9 | 993 (65.2) | 144 (56.9) | 1 | 0.002 | 1 | |
25.0-29.9 | 402 (26.4) | 94 (37.2) | 1.66 (1.25-2.20) | 0.90 (0.61-1.33) | 0.599 | |
≥ 30 | 55 (3.6) | 9 (3.6) | 1.16 (0.56-2.40) | 0.55 (0.24-1.27) | 0.161 | |
Waist circumference (cm) | ||||||
mean ± SD | 82.1 ± 9.7 | 85.2 ± 9.3 | ||||
Male < 90, female < 80 | 1161 (76.2) | 164 (64.8) | < 0.001 | 1 | ||
Male ≥ 90, female ≥ 80 | 362 (23.8) | 89 (35.2) | 1.74 (1.31-2.31) | 1.72 (1.15-2.55) | 0.008 | |
Diabetes mellitus | 55 (3.6) | 16 (6.3) | 1.80 (1.02-3.20) | 0.041 | 1.29 (0.71-2.35) | 0.403 |
Hypertension | 309 (20.3) | 81 (32.0) | 1.85 (1.38-2.48) | < 0.001 | 1.36 (0.92-2.02) | 0.127 |
Metabolic syndrome | 154 (10.1) | 38 (15.0) | 1.57 (1.07-2.30) | 0.020 | 0.88 (0.53-1.46) | 0.612 |
hsCRP (mg/dL) | 128 (8.4) | 22 (8.7) | ||||
< 0.10 | 1004 (65.9) | 156 (61.7) | 1 | 0.187 | ||
≥ 0.10 | 519 (34.1) | 97 (38.3) | 1.20 (0.91-1.58) | |||
Triglyceride (mg/dL) | ||||||
mean ± SD | 119.2 ± 86.4 | 146.2 ± 101.3 | ||||
< 150 | 1168 (76.7) | 165 (65.2) | 1 | < 0.001 | 1 | |
≥ 150 | 355 (23.3) | 88 (34.8) | 1.76 (1.32-2.33) | 1.18 (0.85-1.63) | 0.330 | |
HDL cholesterol (mg/dL) | ||||||
mean ± SD | 58.0 ± 14.8 | 55.4 ± 15.4 | ||||
Male < 40, female < 50 | 162 (10.6) | 30 (11.9) | 1 | 0.563 | ||
Male ≥ 40, female ≥ 50 | 1361 (89.4) | 223 (88.1) | 0.89 (0.59-1.34) | |||
LDL cholesterol (mg/dL) | ||||||
mean ± SD | 135.1 ± 43.0 | 138.7 ± 36.8 | ||||
≤ 100 | 244 (16.0) | 38 (15.0) | 1 | 0.106 | ||
101-129 | 493 (32.4) | 67 (26.5) | 0.87 (0.57-1.34) | |||
≥ 130 | 786 (51.6) | 148 (58.5) | 1.21 (0.82-1.78) | |||
Total cholesterol (mg/dL) | ||||||
mean ± SD | 205.8 ± 38.1 | 210.9 ± 39.6 | ||||
< 200 | 715 (46.9) | 100 (39.5) | 1 | 0.028 | 1 | |
≥ 200 | 808 (53.1) | 153 (60.5) | 1.35 (1.03-1.78) | 1.08 (0.81-1.44) | 0.595 | |
Current alcohol | 637 (41.8) | 133 (52.6) | 1.54 (1.18-2.01) | 0.001 | 1.04 (0.77-1.40) | 0.806 |
Smoking status | ||||||
Never | 639 (42.0) | 66 (26.1) | 1 | < 0001 | 1 | |
Former | 339 (22.3) | 62 (24.5) | 1.77 (1.22-2.57) | 1.23 (0.79 -1.93) | 0.359 | |
Current | 545 (35.8) | 125 (49.4) | 2.22 (1.61-3.06) | 1.60 (1.07-2.41) | 0.023 |
- Citation: Lee SE, Jo HB, Kwack WG, Jeong YJ, Yoon YJ, Kang HW. Characteristics of and risk factors for colorectal neoplasms in young adults in a screening population. World J Gastroenterol 2016; 22(10): 2981-2992
- URL: https://www.wjgnet.com/1007-9327/full/v22/i10/2981.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i10.2981