Characteristics of and risk factors for colorectal neoplasms in young adults in a screening population

Table 1 Baseline characteristics of the subjects according to age n (%)

Variable	Age group				P value
	< 40 (n = 694)	40-44 (n = 591)	45-49 (n = 491)	≥50 (n = 1043)
Males	465 (67.0)	443 (75.0)	363 (73.9)	717 (68.7)	0.790
Body mass index (kg/m2)	23.1 ± 3.3	23.8 ± 3.3	24.0 ± 3.0	24.0 ± 3.0	< 0.001
Waist circumference (cm)	81.5 ± 10.3	82.9 ± 9.5	83.7 ± 8.8	84.1 ± 8.7	< 0.001
Diabetes mellitus	17 (2.4)	21 (3.6)	33 (6.7)	130 (12.5)	< 0.001
Hypertension	89 (12.8)	146 (24.7)	155 (31.6)	462 (44.3)	< 0.001
Metabolic syndrome	48 (6.9)	67 (11.3)	77 (15.7)	226 (21.7)	< 0.001
High hsCRP	54 (7.8)	55 (9.3)	41 (8.4)	131 (12.6)	0.001
Triglyceride (mg/dL)	116.0 ± 91.2	125.4 ± 85.3	130.2 ± 90.2	123.8 ± 83.6	0.039
HDL cholesterol (mg/dL)	58.7 ± 15.1	57.5 ± 14.7	56.3 ± 14.6	56.7 ± 15.1	0.018
LDL cholesterol (mg/dL)	132.0 ± 50.3	136.6 ± 34.1	139.5 ± 36.8	137.4 ± 35.1	0.006
Total cholesterol (mg/dL)	202.1 ± 37.5	208.0 ± 36.0	210.8 ± 41.6	208.2 ± 39.4	0.001
Alcohol consumption	272 (39.2)	263 (44.5)	235 (47.9)	348 (33.4)	0.005
Smoking status
Never	312 (45.0)	212 (35.9)	181 (36.9)	449 (43.0)	< 0.001
Former	134 (19.3)	136 (23.0)	131 (26.7)	366 (35.1)
Current	248 (35.7)	243 (41.1)	179 (36.5)	228 (21.9)
Colorectal adenoma	61 (8.8)	87 (14.7)	105 (21.4)	302 (29.0)	< 0.001
Advanced neoplasm	6 (0.9)	4 (0.7)	6 (1.2)	26 (2.5)	0.004
≥ 1 cm	5 (0.7)	3 (0.5)	5 (1.0)	24 (2.3)	0.001
Villous	1 (0.1)	1 (0.2)	1 (0.2)	7 (0.7)	0.055
High grade	0 (0.0)	1 (0.2)	1 (0.2)	4 (0.4)	0.091
Multiplicity	8 (1.2)	18 (3.0)	33 (6.7)	121 (11.6)	< 0.001

hsCRP: High-sensitivity C-reactive protein; HDL: High-density lipoprotein cholesterol; LDL: Low-density lipoprotein cholesterol.