Gastric cancer: Current status of lymph node dissection

Table 3 Results of randomised controlled trials on D1 vs D2 gastrectomy

RCT	Nr. pts		Morbidity (%)		Mortality (%)		Survival (%)
	D1	D2	D1	D2	D1	D2	D1 (OS)	D2 (OS)
Bonenkamp et al[45,46]	380	331	25	43 P < 0.001	4	10 P = 0.04	45 (5 yr)	47 (5 yr) P = 0.99
							30 (11 yr)	35 (11 yr) P = 0.53
							21 (15 yr)	35 (15 yr) P = 0.03
Cuschieri et al[38,49]	200	200	28	46 P < 0.001	6.5	13 P = 0.04	35 (5 yr)	33 (5 yr) P = 0.43
Wu et al[55,56]	110	111	17.1	7.3 P = 0.012	0	0	59.5 (5 yr)	53.3 (5 yr) P = 0.041
Degiuli et al[18,58]	133	134	12	17.9 P = 0.178	3	2.2 P = 0.722	66.5 (5 yr)	64.2 (5 yr) P = 0.695
							38 (DSS 5 yr T2-T4 N+)	59.0 (DSS 5 yr T2-4 N+) P = 0.055

RCT: Randomised controlled trial; OS: Overall survival; DSS: Disease specific survival; N+: Node positive patients.