Differentiation of hepatocellular carcinoma from its various mimickers in liver magnetic resonance imaging: What are the tips when using hepatocyte-specific agents?

Figure 2 Fat-containing hepatocellular carcinoma in a 57-year-old man with hepatitis B infection. A: Hepatic arterial phase using gadoxetic acid shows heterogeneously arterial enhancement with intralesional low SI area; B: Transitional phase shows washout of the contrast medium in the tumor with capsular enhancement; C: Hepatobiliary phase shows marked hypointensity of the tumor relative to the liver parenchyma; D: T2-weighted image shows high signal intensity of the tumor; E, F: Opposed phase (E) and in-phase (F) T1-weighted gradient echo images reveals area of signal drop on opposed-phase image, indicating fat-containing lesion.