Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma

Figure 2 The relationship between hepatitis B virus-induced autophagy and hepatitis B virus replication. Hepatitis B virus (HBV)-induced autophagy regulates virus replication and maturation at different stages of HBV replication. (I): Autophagy enhances HBV replication at the DNA replication stage; (II): HBV-induced autophagy is required for viral envelopment. However, envelope proteins (HBs) could be eliminated via the autophagic degradation pathway (III).