Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importance

doi:10.3748/wjg.v22.i1.72

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Jan 7, 2016 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2016; 22(1): 72-88
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.72

Table 1 Typical clinical applications for the quantitative assessment of hepatic function by means of ¹³C-labeled compounds as breath test substrates

Investigated function	¹³C-labelled compound
Bile acid malabsorption	Glycocholic acid
Hepatic microsomal function (CYP P450)	Aminopyrine, methacetin, phenacetin caffeine, diazepam, erythromycin
Hepatic cytosolic function (galactokinase)	Galactose, phenylalanine
Hepatic mitochondrial function (α-keto acid dehydrogenase complex)	Methionine, octanoate, α-ketoisocaproic acid

Citation: Dietrich CG, Götze O, Geier A. Molecular changes in hepatic metabolism and transport in cirrhosis and their functional importance. World J Gastroenterol 2016; 22(1): 72-88
URL: https://www.wjgnet.com/1007-9327/full/v22/i1/72.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i1.72