Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis

Table 9 Efficacy of endoscopic therapy for gastrointestinal bleeding from Dieulafoy's lesion in cirrhotics

Endoscopic procedure(Number of patients)	Hemostatictechnique	Lesion location	Study type	Follow-up	Patient outcome	Ref.
EGD (12)1	Epinephrine + Polidocanol	Stomach/duodenum	Retrospective	5 mo	No rebleeding, 3 of cirrhotic pts died from hepatic decompensation within 5 mo	Baettig et al[92]
EGD (6)	Not reported	Stomach/duodenum	Retrospective	NA (6 yr period reviewed)	No rebleeding in 5 of 6 pts (83%), 1 pt (17%) underwent surgery for rebleeding	Akhras et al[91]
EGD (5)	Histoacryl (3)	Stomach	Retrospective	18 mo	No rebleeding	Cheng et al[159]
	Epinephrine + heater probe (2)
EGD (4)	Hemoclip	Stomach/duodenum	Prospective	54 mo	9% of whole cohort of 34 pts rebled. No data whether any of the cirrhotics rebled	Yamaguchi et al[160]
EGD (2)	Rubber band ligation	Stomach	Retrospective	30 d	No rebleeding, 1 of 2 pts died from hepatic decompensation within 30 d	Mumtaz et al[157]
EGD (1)	Argon plasma coagulation	Stomach	Retrospective	29 mo	No rebleeding	Iacopini et al[158]

¹Includes 4 patients with cirrhosis and 8 patients who actively abused alcohol. EGD: Esophagogastroduodenoscopy; pts: Patients.