Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis

Table 2 Clinical characteristics of patients with cirrhosis presenting with upper gastrointestinal bleeding unrelated to portal hypertension predominantly from peptic ulcers

Ref.	No. of parents	ALD (%)	Mean age	Prevalence of PUB (%)	Mortality (%)	Predictors of mortality	Rebleeding rate (%)	Length of follow-up
González-González et al[52]	160	“Most”	56.5 ± 14.4	50.6	13.8	High BUN, Low albumin, Active ulcer bleeding, Need for endoscopic therapy, Cryptogenic cirrhosis	1.9	NA
Seo et al[61]	107	43	55.8 ± 11	60	14.5	Failure to control bleeding, High creatinine, High AST, High Child-Pugh score, PVT	9.3	6 wk
Morsy et al[62]	93	NA	55.3 ± 11.2	30	14	Bacterial infection, Shock, Early rebleeding, Low albumin, Low hemoglobin, Endoscopic therapy	4.3	Short-term (in-hospital)
Siringo et al[22]	85	40	62 ± 12	41	231	Low hemoglobin,	0	6 wk
						Encephalopathy
						Alcoholism, High bilirubin, PVT, High Child-Pugh score,
						High AST/ALT levels, HCC
Rudler et al[63]	29	24 (83)	55.0 ± 9.0	29 (100)2	1 (3)	NA	2 (7)	30 d

¹Mortality from all etiologies of non-variceal GI bleeding;

²PUD presence - study inclusion criteria. BUN: Blood urea nitrogen; PVT: Portal vein thrombosis; AST/ALT: Aspartate aminotransferase/alanine aminotransferase; HCC: Hepatocellular carcinoma; NA: Not available.