Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine

Figure 1 Representative CD10-positive small intestinal adenocarcinoma case. A: Well differentiated adenocarcinoma (pointed by arrows) (HE stain, × 12.5); B: CD10-positive glands were seen in the superficial area and the edge of the adenocarcinoma (left, pointed by arrows), while CD10-negative glands were seen in the center or deep area of the tumor (right) (CD10, × 12.5); C, D: These glands in the surface area were positive for CD10 (HE stain and CD10, × 200); E, F: Other glands in the deeper invasive area were negative for CD10 and showed more evident loss of nuclear polarity compared to the CD10-positive glands (HE stain and CD10, × 200).