Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine

doi:10.3748/wjg.v21.i9.2700

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2015; 21(9): 2700-2710
Published online Mar 7, 2015. doi: 10.3748/wjg.v21.i9.2700

Table 3 Clinicopathological features and expression of mucin core proteins and CD10

	MUC5AC		MUC6		MUC2		CD10
	Positive(n = 12)	Negative(n = 35)	Positive(n = 4)	Negative(n = 43)	Positive(n = 20)	Negative(n = 27)	Positive(n = 7)	Negative(n = 40)
Age (yr)
Mean ± SD	63.4 ± 15.1¹	58.8 ± 16.5	76.3 ± 10.0¹	58.7 ± 15.9	62.3 ± 15.3	58.0 ± 16.7¹	60.1 ± 15.1	59.8 ± 16.5¹
(range)	(35-85)	(23-87)	(67-87)	(23-85)	(38-87)	(23-81)	(38-87)	(23-85)
Gender (male/female)	10/2	19/16	3/1	26/17	9/11	18/9	3/4	27/14
Gross appearance
(polypoid/ulcerated)	3/9	9/26	2/2	10/33	6/14	6/21	4/3^a	8/32^a
Size (cm)	5.3 ± 2.2	5.1 ± 1.9	5.0 ± 1.8	5.1 ± 2.0	5.7 ± 1.6^a	4.7 ± 2.2^a	5.9 ± 1.4^a	5.0 ± 2.1^a
Location
(duodenum/jejunum/ileum)	2/5/5	12/16/7	2/1/1	12/20/11	6/11/3	8/10/9	4/2/1	10/19/11
Histological subtype
(tubular²/poorly/mucinous)	6/3/3	27/6/2	3/0/1	30/9/4	13/2/5	10/7/0	7/0/0	29/9/5
Invasion depth³
T1	0	2	0	2	2	0	2^a	0^a
T2	2	2	2	2	2	2	2^a	2^a
T3	2	16	0	18	6	12	1^a	17^a
T4	8	15	2	21	10	13	2^a	21^a
Lymphatic permeation n (%)	10 (83)	23 (66)	2 (50)	31 (72)	12 (60)	21 (78)	3 (43)	30 (75)
Venous invasion n (%)	3 (25)	9 (26)	1 (25)	11 (26)	5 (25)	7 (26)	2 (29)	10 (25)
Adenomatous component n (%)	0 (0)	3 (9)	1 (25)	2 (5)	3 (15)^a	0 (0)^a	2 (29)^a	1 (3)^a

¹Age of one patient was unknown;

²"tubular" contains well or moderately differentiated adenocarcinoma;

³UICC TNM classification is used.

^aP < 0.05 vs positive group and negative group in the same mucin core protein or CD10. In comparison invasion depth, T1 vs T2-T4).

Citation: Kumagai R, Kohashi K, Takahashi S, Yamamoto H, Hirahashi M, Taguchi K, Nishiyama K, Oda Y. Mucinous phenotype and CD10 expression of primary adenocarcinoma of the small intestine. World J Gastroenterol 2015; 21(9): 2700-2710
URL: https://www.wjgnet.com/1007-9327/full/v21/i9/2700.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i9.2700