Absolute monocyte and lymphocyte count prognostic score for patients with gastric cancer

Table 3 Clinical characteristics according to the absolute monocyte count/absolute lymphocyte count prognostic score in patients with gastric cancer

Variable	Low risk (n = 158)4		Intermediate risk (n = 128)4		High risk (n = 13)4		P value
	n (%)	Mean ± SD	n (%)	Mean ± SD	n (%)	Mean ± SD
Age (yr)		56.4 ± 10.71		61.2 ± 12.22		64.0 ± 10.11,2	0.0006
Gender							0.2602
Male	99 (62.7)		85 (66.4)		11 (84.6)
Female	59 (37.3)		43 (33.6)		2 (15.4)
Tumor size (cm)		3.7 ± 2.91		4.3 ± 3.21		7.1 ± 5.12	0.0005
T category							0.0008
T1-2	117 (74.1)		76 (59.4)		4 (30.8)
T3-4	41 (25.9)		52 (40.6)		9 (69.2)
N category							0.0565
N0	111 (70.3)		83 (64.8)		5 (38.5)
N1-3	47 (29.7)		45 (35.2)		8 (61.5)
TNM stage							0.0200
I-II	133 (84.2)		99 (77.3)		7 (53.8)
III	25 (15.8)		29 (22.7)		6 (46.2)
Lymphatic invasion							0.0102
Negative	117 (74.1)		81 (63.3)		5 (38.5)
Positive	41 (25.9)		47 (36.7)		8 (61.5)
Vascular invasion							0.0105
Negative	156 (98.7)		120 (93.8)		11 (84.6)
Positive	2 (1.3)		8 (6.3)		2 (15.4)
Albumin (g/dL)		4.2 ± 0.31		4.0 ± 0.42		3.7 ± 0.53	< 0.0001
AMC (/μL)		459.1 ± 110.01		478.3 ± 226.91		765.5 ± 93.92	< 0.0001
ALC (/μL)		2283.8 ± 423.11		1661.2 ± 685.92		1444.9 ± 219.52	< 0.0001
Hemoglobin (g/dL)		13.4 ± 1.91		12.4 ± 2.32		10.2 ± 2.53	< 0.0001
Platelet (× 103/μL)		248.8 ± 66.61		238.7 ± 78.01		270.1 ± 67.01	0.2219
MPV (fL)		8.0 ± 0.91		7.9 ± 0.81		7.6 ± 0.91	0.2373
NLR		1.7 ± 0.71		2.9 ± 2.62		4.2 ± 2.62	< 0.0001
PLR		111.8 ± 35.31		165.0 ± 116.32		191.6 ± 58.32	< 0.0001

^1,2,3Means with the same letter are not significantly different;

⁴AMLPS (AMC/ALC prognostic score) was defined as low-risk (both AMC ≤ 672.4/μL and ALC > 1734/μL), intermediate-risk (either AMC > 672.4/μL or ALC ≤ 1734/μL) and high-risk (both AMC > 672.4/μL and ALC ≤ 1734/μL). P values for comparison of mean difference for continuous variables were obtained by analysis of variance with post-hoc test of Scheffe; P values for independent test for categorical variables were obtained by χ² test. TNM: Tumor node metastasis; SD: Standard deviation; ANC: Absolute neutrophil count; AMC: Absolute monocyte count; ALC: Absolute lymphocyte count; MCV: Mean corpuscular volume; MPV: Mean platelet volume; NLR: Neutrophil/lymphocyte count ratio; PLR: Platelet/lymphocyte count ratio.