Outcomes of nonresected main-duct intraductal papillary mucinous neoplasms of the pancreas

Table 4 Analysis of prognostic factors in 124 patients with a resected or nonresected main-pancreatic duct and mixed intraductal papillary mucinous neoplasm of the pancreas

Variable (n)	Univariate analyses by log-rank test		Multivariate analyses by Cox’s model
	RR (95%CI)	P value	HR (95%CI)	P value
Surgery		0.02		0.08
No (50)	1		1
Yes (74)	0.48 (0.26-0.88)		0.54 (0.27-1.09)
Age at diagnosis		0.01		0.13
< 70 yr (83)	1		1
≥ 70 yr (41)	2.36 (1.26-4.40)		1.72 (0.86-3.46)
Extra-pancreatic cancer		0.13		-
No (98)	1		-
Yes (26)	1.66 (0.86-3.22)		-
MPD size > 10 mm		0.13		-
No (100)	1		-
Yes (24)	1.66 (0.86-3.22)		-
Nodule1		0.01		0.01
No (88)	1		1
Yes (36)	2.42 (1.17-5.00)		2.71 (1.29-5.69)
BD size > 30 mm		0.85		-
No (94)	1		-
Yes (30)	1.08 (0.51-2.29)		-
Fortuitous		0.63		-
No (96)	1		-
Yes (28)	1.19 (0.58-2.45)		-
Acute pancreatitis		0.24		-
No (79)	1		-
Yes (45)	0.68 (0.35-1.30)		-

¹Nodule and wall thickening of MPD and/or branch-duct cysts. BD: Branch duct; MPD: Main pancreatic duct.