Outcomes of nonresected main-duct intraductal papillary mucinous neoplasms of the pancreas

Table 1 Main characteristics of patients n (%)

Characteristic	Total population, n = 124	Surgical patients, n = 74	Nonsurgical patients, n = 50	P value1
Age at diagnosis (yr), mean ± SD (range)	64.4 ± 9.0 (33-82)	61.2 ± 7.0 (33-73)	69.0 ± 8.0 (58-2)	< 0.01
Sex ratio, male:female	74:50	46:28	28:22	0.57
Associated non-pancreatic cancers2	26 (22.0)	10 (13.5)	16 (32.0)	0.02
Symptoms	96 (77.5)	61 (82.5)	35 (70.0)	0.12
Acute pancreatitis	45 (36.0)	32 (43.0)	13 (36.0)	0.06
Diabetes	15 (12.0)	12 (16.0)	3 (6.0)	0.10
Jaundice	13 (10.4)	7 (13.5)	6 (12.0)	0.76
Others	23 (18.5)	10 (13.5)	13 (26.0)	0.10
Fortuitous	28 (22.5)	13 (17.5)	15 (30.0)	0.12
Localization of IPMN
Head	93 (75.0)	58 (78.5)	35 (70.0)	0.29
Body	12 (9.5)	6 (8.5)	6 (12.0)	0.54
Tail	10 (8.0)	5 (6.5)	5 (10.0)	0.52
Diffuse	9 (7.5)	5 (6.5)	4 (8.0)	1.00
Involvement of branch duct (mixed forms)	101 (81.5)	59 (79.0)	42 (84.0)	0.64
Maximal diameter of main duct at diagnosis, mm	7.6 ± 0.4 (6)	7.2 ± 0.4 (6)	8.3 ± 0.9 (6)	0.19
mean ± SD (median)
Tissue nodule or wall thickening at imaging3	36 (29.0)	21 (28.0)	15 (30.0)	0.84
Malignant invasive IPMN	62 (50.0)	41 (55.5)	21 (40.0)4	0.19
Follow-up after diagnosis (mo), median (range)	24 (162-6)	24 (162-9)	30 (141-6)	0.85
Death	41 (33.0)	19 (26.0)	22 (44.0)	0.05

¹Nonsurgical vs surgical groups;

²Lung: n = 5, prostate: n = 7, hemopathy: n = 3, mammary: n = 3, colon: n = 2, miscellaneous: n = 6;

³Main pancreatic duct or branch-duct cyst, or both, mainly visualized by endoscopic ultrasound;

⁴Occurrence during follow-up in 18 patients. IPMN: Intraductal papillary mucinous neoplasm.