Meta-analysis: Is combination of tetracycline and amoxicillin suitable for Helicobacter pylori infection?

Table 2 Characteristics of included studies in triple

Ref.	Region	Publication	Participants	H. pylori infection Initial diagnosis⁄re-checking	Inventions (duration)	Total (treatment/control)	Follow-up (wk)	Eradication rate by ITT	Jadad scores
Laine et al[33] 1995	United States	Full text	Volunteers with H. pylori infection	UBT/UBT	OAT 14 vs OA 14	30/30	4	30% vs 50%	3
Perri et al[24], 2003	Italy	Full text	NR	UBT/UBT	RBCAT 7 vs PLA or PBMT 7	60/120	4-6	85% vs 73.3%	3
Uygun et al[21], 2007	Turkey	Full text	Non-ulcer Dyspeptic patients	Histology and UBT/UBT	RBCAT 14 vs RBCAC or RBCMT 14	100/200	6	58% vs 58%	3
Chuah et al[50], 2012	Taiwan	Full text	Peptic ulcer disease or gastritis	RUT/RUT and histology or UBT	EAT 14 vs EALe 14	64/64	8	75% vs 78%	3
Zhao[17], 2013	China	Full text	peptic ulcer and chronic gastritis	NR/UBT	PAT 7/PAC or PAM or PAF or PALe 7	34/138	30 d	94% vs 73%	1

NR: Not reported; UBT: Urea breath test; RUT: Rapid urease test; O: Omeprazole; A: Amoxicillin; T: Tetracycline; B: Bismuth; C: Clarithromycin; M: Metrodinazole; P: Pantoprazole; E: Esomeprazole; L: Lansoprazole; D: Doxycycline; F: Furazolidone; Le: Levofloxacin; RBC: Ranitidine bismuth citrate.