Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors

Table 4 Observation in patients with unresectable metastatic well-differentiated pancreatic neuroendocrine tumors

Rate the appropriateness of observation without regional or medical therapy	In a patient whose primary problem is:
	Uncontrolled secretory symptoms	Uncontrolled tumor-related symptoms	Rapid radiographic progression	Nonrapid radiographic progression	No symptoms and no radiographic progression
	1.01 (0.0)	1.01 (0.0)	1.01 (0.0)	4.32 (1.2)	8.03 (1.3)

The medians of ratings represents the type of panel consensus that was reached for the particular patient scenario (cell).

¹Median rating 1-3 and no disagreement⁴ = “inappropriate”;

²Median rating 4-6 and no disagreement⁴ = “uncertain”; and

³Median rating 7-9 and no disagreement⁴ = “appropriate”; ⁴ > 2 responses in the range 1-3 and > 2 responses in the range 7-9 = “disagreement”.