Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma

doi:10.3748/wjg.v21.i8.2433

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2015; 21(8): 2433-2442
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2433

Table 6 Factors retaining prognostic significance for progression-free survival and overall survival with multivariate and Cox proportional hazards analysis

Prognostic factors	OS			PFS
Prognostic factors	HR	95%CI	P	HR	95%CI	P
Age	1.570	0.384-6.430	0.530	0.403	0.132-1.224	0.109
Lugano staging system	0.253	0.009-6.990	0.417	1.091	0.243-4.893	0.910
IPI	13.246	2.929-59.903	0.001	15.302	4.119-56.845	< 0.0001
Treatment	1.374	0.247-7.625	0.717	1.542	0.522-4.555	0.434
BCL-2 protein expression	1.056	0.029-37.972	0.976	1.773	0.154-20.434	0.646
MYC/BCL-2 coexpression	4.435	0.728-26.994	0.106	11.371	1.264-102.295	0.030

OS: Overall survival; PFS: Progression-free survival; IPI: International prognostic index.

Citation: Xia B, Zhang L, Guo SQ, Li XW, Qu FL, Zhao HF, Zhang LY, Sun BC, You J, Zhang YZ. Coexpression of MYC and BCL-2 predicts prognosis in primary gastrointestinal diffuse large B-cell lymphoma. World J Gastroenterol 2015; 21(8): 2433-2442
URL: https://www.wjgnet.com/1007-9327/full/v21/i8/2433.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i8.2433