Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Feb 28, 2015; 21(8): 2405-2412
Published online Feb 28, 2015. doi: 10.3748/wjg.v21.i8.2405
Table 6 Relationships between polyunsaturated fatty acid tissue levels and clinicopathologic parameters in colorectal carcinoma
Clinicopathologic parameterThe number of casesLA (%)DGLA (%)AA (%)ALA (%)EPA (%)DPA (%)DHA (%)ω-3PUFA (%)ω-6/ω-3 PUFAAA/ω-3 PUFAω-6 PUFA(%)AA/ω-6 PUFAAA/LA
Sex
Male5115.3 ± 2.81.37 ± 0.650.15 ± 0.080.23 ± 0.130.24 ± 0.110.51 ± 0.181.32 ± 0.561.56 ± 0.6512.2 ± 5.55.9 ± 2.724.9 ± 3.00.32 ± 0.100.55 ± 0.21
Female3116.1 ± 4.51.24 ± 0.770.13 ± 0.070.35 ± 0.180.25 ± 0.140.47 ± 0.271.35 ± 0.741.59 ± 0.4811.6 ± 3.84.9 ± 1.824.7 ± 3.80.29 ± 0.100.49 ± 0.23
Age (yr)
< 603815.8 ± 3.41.38 ± 0.800.17 ± 0.09a0.23 ± 0.120.23 ± 0.110.50 ± 0.191.34 ± 0.551.57 ± 0.6312.0 ± 4.05.6 ± 2.525.3 ± 2.90.31 ± 0.080.53 ± 0.20
≥ 604415.4 ± 3.61.27 ± 0.590.12 ± 0.06a0.32 ± 0.160.25 ± 0.160.48 ± 0.241.33 ± 0.711.58 ± 0.8311.9 ± 5.75.5 ± 2.424.4 ± 3.50.31 ± 0.100.52 ± 0.23
Location
Colon4415.3 ± 3.31.30 ± 0.570.14 ± 0.070.26 ± 0.150.23 ± 0.140.50 ± 0.291.37 ± 0.721.61 ± 0.8212.3 ± 5.95.6 ± 2.524.6 ± 3.40.32 ± 0.090.54 ± 0.22
Rectum3815.9 ± 3.81.34 ± 0.820.15 ± 0.060.30 ± 0.120.26 ± 0.150.48 ± 0.171.28 ± 0.531.56 ± 0.6511.6 ± 3.65.4 ± 2.425.0 ± 3.10.30 ± 0.090.51 ± 0.21
Tumor size (cm)
< 54215.5 ± 4.11.37 ± 0.780.15 ± 0.070.31 ± 0.130.29 ± 0.13a0.50 ± 0.211.32 ± 0.491.61 ± 0.5910.8 ± 2.6a5.0 ± 2.024.9 ± 3.50.31 ± 0.100.54 ± 0.23
≥ 54015.6 ± 2.81.27 ± 0.600.14 ± 0.060.24 ± 0.120.20 ± 0.14a0.48 ± 0.291.34 ± 0.761.54 ± 0.8813.2 ± 6.4a6.0 ± 2.824.7 ± 3.00.31 ± 0.080.51 ± 0.20
Differentiation degree
High2415.6 ± 2.6a1.18 ± 0.430.14 ± 0.060.26 ± 0.120.22 ± 0.120.46 ± 0.241.28 ± 0.721.49 ± 0.8013.5 ± 4.96.6 ± 3.2a25.0 ± 3.00.31 ± 0.090.53 ± 0.22
Middle5315.1 ± 3.3a1.41 ± 0.780.15 ± 0.070.26 ± 0.140.26 ± 0.140.51 ± 0.261.37 ± 0.611.62 ± 0.7311.4 ± 3.95.2 ± 1.9a24.4 ± 3.40.31 ± 0.080.54 ± 0.20
Low519.9 ± 6.3a1.09 ± 0.600.15 ± 0.040.58 ± 0.200.23 ± 0.120.46 ± 0.141.24 ± 0.541.47 ± 0.6711.4 ± 2.44.1 ± 2.0a27.9 ± 2.40.25 ± 0.150.41 ± 0.32
Clinicopathologic stage
I + II3514.9 ± 3.01.46 ± 0.850.15 ± 0.090.21 ± 0.130.25 ± 0.130.52 ± 0.221.42 ± 0.551.67 ± 0.6411.2 ± 3.75.1 ± 1.924.5 ± 3.10.32 ± 0.080.56 ± 0.22
III + IV4716.1 ± 3.81.22 ± 0.530.14 ± 0.100.33 ± 0.180.24 ± 0.140.47 ± 0.271.27 ± 0.691.51 ± 0.8112.6 ± 5.65.8 ± 2.725.0 ± 3.50.30 ± 0.100.50 ± 0.22
Lymph node metastasis
Negative4014.9 ± 3.11.37 ± 0.830.13 ± 0.100.21 ± 0.130.24 ± 0.140.47 ± 0.251.32 ± 0.581.55 ± 0.6612.5 ± 5.05.7 ± 2.624.3 ± 2.90.32 ± 0.080.56 ± 0.23
Positive4216.2 ± 3.81.27 ± 0.540.15 ± 0.090.34 ± 0.140.25 ± 0.130.51 ± 0.251.35 ± 0.691.60 ± 0.8211.5 ± 3.65.4 ± 2.225.3 ± 3.60.30 ± 0.090.50 ± 0.21
VEGF
Positive5716.2 ± 3.7ab1.32 ± 0.670.15 ± 0.070.30 ± 0.140.26 ± 0.130.48 ± 0.231.34 ± 0.531.60 ± 0.6411.6 ± 3.75.0 ± 1.8b25.2 ± 3.00.30 ± 0.09a0.50 ± 0.21a
Negative2313.9 ± 2.7ab1.33 ± 0.790.11 ± 0.050.23 ± 0.120.22 ± 0.110.52 ± 0.301.33 ± 0.651.54 ± 0.9812.6 ± 7.16.7 ± 3.3b23.7 ± 3.90.34 ± 0.09a0.61 ± 0.21a
Ki-67
-222.5 ± 10.1a0.92 ± 0.820.04 ± 0.021.02 ± 0.550.25 ± 0.11ab0.31 ± 0.021.25 ± 0.851.49 ± 1.4110.6 ± 1.33.1 ± 2.529.9 ± 1.20.22 ± 0.280.41 ± 0.25
+415.8 ± 2.7a1.50 ± 0.310.19 ± 0.070.17 ± 0.070.26 ± 0.11ab0.55 ± 0.161.79 ± 0.512.04 ± 0.639.9 ± 2.64.5 ± 1.126.2 ± 2.30.33 ± 0.040.56 ± 0.12
++616.3 ± 4.5a1.93 ± 1.510.20 ± 0.110.30 ± 0.070.36 ± 0.17ab0.55 ± 0.231.26 ± 0.891.62 ± 0.9712.4 ± 6.25.3 ± 2.325.5 ± 2.20.28 ± 0.080.49 ± 0.28
+++2315.9 ± 3.1a1.34 ± 0.560.12 ± 0.060.28 ± 0.080.29 ± 0.13ab0.50 ± 0.311.33 ± 0.681.62 ± 0.7811.7 ± 3.45.5 ± 2.525.3 ± 2.70.31 ± 0.090.54 ± 0.23
++++4615.0 ± 3.1a1.23 ± 0.600.15 ± 0.070.25 ± 0.160.21 ± 0.12ab0.48 ± 0.231.32 ± 0.581.53 ± 0.7012.1 ± 5.65.7 ± 2.524.1 ± 3.60.31 ± 0.080.53 ± 0.20
p53
+3215.6 ± 3.71.40 ± 0.840.15 ± 0.090.25 ± 0.130.22 ± 0.130.55 ± 0.221.46 ± 0.681.68 ± 0.7911.9 ± 6.55.5 ± 2.725.2 ± 2.80.32 ± 0.090.55 ± 0.22
++715.2 ± 4.21.70 ± 0.860.18 ± 0.110.23 ± 0.120.24 ± 0.090.58 ± 0.271.32 ± 0.321.56 ± 0.4110.8 ± 2.44.9 ± 1.324.6 ± 3.00.31 ± 0.090.55 ± 0.25
+++2815.2 ± 3.31.27 ± 0.550.17 ± 0.110.28 ± 0.140.26 ± 0.110.50 ± 0.241.32 ± 0.671.58 ± 0.8211.6 ± 3.95.4 ± 2.324.2 ± 4.30.30 ± 0.070.50 ± 0.19