Outcome of transarterial chemoembolization-based multi-modal treatment in patients with unresectable hepatocellular carcinoma

Table 4 Pre-treatment prognostic factors for survival in the treatment group

Factors	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Age (< 60 yr vs≥ 60 yr)	0.634	0.393-1.023	0.062
Gender (female vs male)	0.768	0.373-1.584	0.475
Child-Turcotte-Pugh score (5 vs 6)	1.292	0.839-1.990	0.245
AFP (< 1000 ng/mL vs≥ 1000 ng/mL)	1.346	0.914-1.982	0.132
Maximal tumor size (< 15 cm vs≥ 15 cm)	1.342	0.842-2.140	0.216
Tumor type (well-demarcated vs poorly-demarcated)	2.689	1.721-4.203	< 0.001	1.849	1.165-2.934	0.009
Portal vein thrombosis (absent vs present)	2.430	1.519-3.888	< 0.001
Stage (III vs IV-A)	3.344	2.108-5.304	< 0.001	2.828	1.740-4.595	< 0.001

AFP: Alpha-fetoprotein.