Mixed adenoneuroendocrine carcinoma of the ampulla: Two case reports

Figure 4 Histological data of Case 2. A: Poorly differentiated adenocarcinoma admixed with neuroendocrine components (HE staining, × 100); B: The neuroendocrine components: large cells were characteristic for abundant cytoplasm and nuclear hyperchromatism (HE staining, × 100); C: The neuroendocrine carcinoma cells show high mitotic rate (HE staining, × 400); D: Immunohistochemical assay for Ki67 showing high proliferating index (× 100).