Mixed adenoneuroendocrine carcinoma of the ampulla: Two case reports

Figure 2 Histological data of Case 1. A: Poorly differentiated adenocarcinoma admixed with neuroendocrine components [hematoxylin and eosin (HE) staining, × 100]; B: The neuroendocrine component was arranged into a nest and the large cells were consistent in size with round nuclei, abundant cytoplasm and coarse chromatin (HE staining, × 100); C: The neuroendocrine carcinoma cells show high mitotic rate (HE staining, × 400); D: Immunohistochemical assay for Ki67 showing high proliferating index (× 100).