Negative impact of bone-marrow-derived mesenchymal stem cells on dextran sulfate sodium-induced colitis

Table 2 Clinical trials of adipose-derived stem cells and mesenchymal stem cells inflammatory bowel disease therapies

Ref.	Disease	Phase	No. of patients	Stem cell source	Route	Outcome
de la Portilla et al[15]	Complex perianal fistula	I/II	24	ASC; Allo-adipose	Intralesional	Improved
Lee et al[20]	Crohn’s fistula	II	43	ASC; Allo-adipose	Intralesional	Improved
Cho et al[13]	Crohn’s fistula	I	10	ASC; Allo-adipose	Intrafistula	Improved
Herreros et al[19]	Complex cryptoglandular perianal fistula	III	200	ASC; Allo-adipose	Intrafistula	Improved
Guadalajara et al[18]	Complex perianal fistula	II	24	ASC; Allo-liposuction	Intrafistula	Improved
Ciccocioppo et al[14]	Crohn’s fistula	I/II	12	MSC; Allo-BM	Intrafistula	Improved
Garcia-Olmo et al[17]	Complex perianal fistula	II	14	ASC; Auto-adipose	Intrafistula	Improved
García-Olmo et al[16]	Crohn’s fistula	I	10	ASC; Allo-adipose	Intrafistula	Improved

ASC: Adipose-derived stem cells; MSC: Mesenchymal stem cells.