Human cytomegalovirus and Epstein-Barr virus infection in inflammatory bowel disease: Need for mucosal viral load measurement

Figure 7 Median values of human Cytomegalovirus (panel A) and Epstein Barr virus (panel B) DNA levels of each refractory patient at onset and at the end of antiviral therapy in human Cytomegalovirus cases, and at four weeks after washout or reduction of current treatment in patients with Epstein-Barr virus infection. A dramatic decrease of mucosal viral loads was observed in all patients with HCMV colitis, except one who continued steroid therapy while taking ganciclovir. By contrast, no modification of mucosal viral load values was observed in any patient with EBV colitis, except the one who underwent a cycle of therapy with rituximab. HCMV: Human Cytomegalovirus; EBV: Epstein Barr virus.