Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis

Table 4 Primary sclerosing cholangitis - inflammatory bowel disease and liver transplantation n (%)

Ref.	n	Pre-OLT			Post-OLT
		PSC only	PSC-IBD	Intact colon1	De novo IBD	Exacerbation	Colectomy	Refractory IBD	Median follow-up (yr)
Dvorchik et al[65], 2002	192	0	192	169 (88.0)	NA	22 (13.0)	33 (19.5)	22 (66.7)	5.93
Haagsma et al[59], 2003	48	25 (52.1)	23 (47.9)	23 (100.0)	6 (24.0)	9 (39.1)	1 (4.3)	0	7.2
Verdonk et al[88], 2006	60	15 (25.0)	45 (75.0)	45 (100.0)	3 (20.0)	NA	NA	NA	6.1
Cholongitas et al[62], 20072	56	18 (32.1)	38 (67.9)	33 (68.8)	3 (16.6)	17 (51.5)	7 (16.7)	3 (42.9)	2.8
Moncrief et al[61], 2010	59	16 (27.1)	42 (71.2)	32 (76.2)	5 (31.3)	13 (40.6)	6 (18.8)	4 (66.7)	5.6
Joshi et al[60], 2011	110	36 (32.7)	74 (67.3)	65 (87.8)	6 (16.7)	33 (50.8)	7 (10.8)	6 (85.7)	6.53
Navaneethan et al[63], 2012	77	0	77	58 (75.3)	NA	5 (8.6)	9 (15.5)	3 (33.3)	5.0
Mosli et al[64], 2013	105	77 (73.3)	28 (26.7)	24 (85.7)	1 (1.3)	6 (25.0)	2 (8.3)	0	7.33

¹Patients with PSC-IBD and without proctocolectomy prior to OLT;

²Study population corrected for survival > 1 year after OLT (n = 56, 18 PSC only, 33 PSC-IBD, 5 PSC-IBD with pre-OLT colectomy, extracted from paper);

³Mean instead of median. OLT: Orthotopic liver transplantation; PSC: Primary sclerosing cholangitis; IBD: Inflammatory bowel disease; NA: Not available.