Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis

Table 1 Epidemiology primary sclerosing cholangitis - inflammatory bowel disease n (%)

Ref.	Country	Period	Incidence1	PSC	Male Gender	PSC-IBD	PSC-UC	PSC-CD	PSC-IBD-U	Diagnosis IBD
Rabinovitz et al[100], 1990	United States	NA	NA	66	NA	47 (71.2)	39 (83.0)	8 (17.0)	0	IBD23
Farrant et al[19], 1991	United Kingdom	1972-1989	NA	126	78 (61.9)	85 (67.5)	83 (97.6)	2 (2.4)	NA	IBD2
Schrumpf et al[18], 1994	Norway	1975-1989	NA	77	51 (66.2)	76 (98.7)	58 (76.3)	11 (14.5)	7 (9.2)	IBD23
Escorsell et al[17], 1994	Spain	1984-1988	0.07	43	26 (60.5)	20 (46.5)	19 (95.0)	1 (5.0)	NA	IBD4
Broomé et al[2], 1996	Sweden	? - 1992	NA	305	195 (63.9)	249 (81.6)	220 (88.4)	20 (8.0)	9 (3.6)	IBD2
Boberg et al[4], 1998	Norway	1986-1995	1.31	17	12 (70.6)	12 (70.6)	9 (75.0)	2 (16.7)	1 (8.3)	IBD4
Ponsioen et al[20], 2002	The Netherlands	1979-1999	NA	174	105 (60.3)	114 (65.5)	83 (72.8)	28 (24.6)	3 (2.6)	IBD4
Bambha et al[5], 2003	United States	1976-2000	0.90	22	15 (68.3)	16 (72.7)	12 (75.0)	3 (18.8)	1 (5.0)	IBD2
Kingham et al[101], 2004	United Kingdom	1984-2003	0.91	53	33 (62.3)	33 (62.3)	30 (90.9)	3 (19.1)	0	IBD4
Bergquist et al[102], 2005	Sweden	1984-1999	NA	145	100 (69.0)	126 (86.9)	107 (84.9)	19 (15.1)	0	IBD23
Tischendorf et al[103], 2007	Germany	1978-2004	NA	273	195 (71.4)	172 (63.0)	141 (82.0)	29 (16.9)	2 (1.2)	IBD23
Bergquist et al[104], 2007	Sweden	1984-2004	NA	246	165 (67.1)	195 (79.3)	166 (85.1)	21 (10.8)	8 (4.1)	IBD23
Kaplan et al[14], 2007	Canada	2000-2005	0.92	49	27 (55.1)	36 (73.5)	17 (47.2)	19 (52.8)	0	IBD23
Card et al[3], 2008	United Kingdom	1987-2002	0.41	223	141 (63.2)	108 (48.4)	67 (62.0)	13 (12.0)	28 (25.9)	IBD4
Lindkvist et al[105], 2010	Sweden	1992-2005	1.22	199	142 (71.4)	152 (76.4)	129 (84.9)	17 (11.2)	5 (3.3)	IBD4
Bowlus et al[106], 2010	United States	1995-2009	NA	6767	4475 (66.1)	4637 (68.5)	3067 (66.1)	1090 (23.5)	480 (10.4)	IBD4
Toy et al[107], 2011	United States	2000-2006	0.41	169	101 (59.8)	109 (64.5)	95 (87.2)	13 (11.9)	1 (0.9)	IBD4
Boonstra et al[22], 2013	The Netherlands	2000-2007	0.50	590	375 (63.6)	402 (68.1)	308 (76.6)	78 (19.4)	16 (4.0)	IBD23

¹Incidence for PSC per 100000 people;

²IBD Endoscopic findings;

³IBD Histological findings (biopsies);

⁴IBD diagnosis not specified/medical records only. PSC: Primary sclerosing cholangitis; UC: Ulcerative colitis; CD: Crohns disease; IBD-U: Inflammatory bowel disease unclassified; NA: Not available.