Incidence and psychological-behavioral characteristics of refractory functional dyspepsia: A large, multi-center, prospective investigation from China

doi:10.3748/wjg.v21.i6.1932

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2015; 21(6): 1932-1937
Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1932

Table 2 Psychological and behavioral characteristics and quality of life of the study subjects n (%)

Characteristic	RFD	NRFD	Healthy volunteers (n = 100)	P value
Characteristic	(n = 327)	(n = 1014)	Healthy volunteers (n = 100)	P value
Depression symptoms	207 (63.3)^a^c	212 (20.9)^c	10 (10.0)	0.002
Mild	112 (34.3)^a^c	170 (16.8)	10 (10.0)	0.001
Moderate	61 (18.7)^a^c	34 (3.4)	0 (0)	0.001
Severe	34 (10.4)^a^c	8 (0.8)	0 (0)	0.004
HAMD score	11.65 ± 6.51^a^c	7.15 ± 3.34^c	1.66 ± 2.50	0.003
Anxiety symptoms	201 (61.5)^a^c	236 (23.3)^c	10 (10.0)	0.002
Mild	97 (29.7)^a^c	162 (16)	10 (10.0)	0.001
Moderate	74 (22.6)^a^c	60 (5.9)^c	0 (0)	0.003
Severe	30 (9.2)^a^c	14 (1.4)	0 (0)	0.001
HAMA score	10.84 ± 5.82)^a^c	6.83 ± 3.53)^c	2.26 ± 2.68	0.001
Both depression and anxiety symptoms	186 (56.9)^a^c	171 (16.9)^c	6 (6.0)	0.001
Eating behavior
Skip meals	68 (20.8)^a^c	131 (12.9)^c	4 (4.0)	0.010
Eating late	92 (28.1)^a^c	222 (21.9)^c	6 (6.0)	0.001
Eating extra meal	30 (9.2)^a^c	55 (5.4)^c	3 (3.0)	0.010
Physical activity level
High	98 (30.0)^c	332 (32.7)^c	44 (44.0)	0.030
Moderate	156 (47.7)	536 (52.9)	54 (54.0)	0.240
Low	73 (22.3)^a^c	146 (14.4)^c	2 (2.0)	0.001
Working time
Working in the day	160 (48.9)	529 (52.2)	56 (56.0)	0.400
Working at night	22 (6.7)	101 (10.0)^c	2 (2.0)	0.010
No work	126 (38.5)^b	333 (32.8)	25 (25.0)	0.030
Sleeping disorder	204 (62.4)^a^c	334 (32.9)^c	13 (13.0)	0.001
PSQI score	8.87 ± 5.00^a^c	5.70 ± 4.12^c	2.95 ± 2.78	0.001
SF-36 score	61.17 ± 16.77^a^c	74.96 ± 13.51^c	88.18 ± 7.30	0.001
Number of times seeking medical advice	13.41 ± 7.66	4.09 ± 2.20	-	0.002
Cost of treatments	3797.28 ± 1406.41	1523.07 ± 665.35	-	0.001

Continuous data are expressed as mean ± SD, and were compared across groups using one-way ANOVA and Student-Newman-Keuls test for multiple comparisons. Count data were compared across groups using a χ² test.

^aP < 0.05 vs NRFD patients;

^cP < 0.05 vs healthy volunteers. RFD: Refractory functional dyspepsia; NRFD: Non-refractory functional dyspepsia; HAMA: Hamilton Anxiety Scale; HAMD: Hamilton Depression Scale; PSQI: Pittsburgh Sleep Quality Index; SF-36: MOS 36-item Short Form Health Survey.

Citation: Jiang SM, Jia L, Lei XG, Xu M, Wang SB, Liu J, Song M, Li WD. Incidence and psychological-behavioral characteristics of refractory functional dyspepsia: A large, multi-center, prospective investigation from China. World J Gastroenterol 2015; 21(6): 1932-1937
URL: https://www.wjgnet.com/1007-9327/full/v21/i6/1932.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i6.1932