Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Feb 14, 2015; 21(6): 1794-1803
Published online Feb 14, 2015. doi: 10.3748/wjg.v21.i6.1794
Table 3 Classification of the ten novel mutants according to the secretion level of hepatitis B surface antigen and viral DNA formation capacity
GroupingMutantssAg level
Viral DNA level
ExtracellularIntracellularExtracellularIntracellular
ITNPositivePositiveHigher than WTSimilar to WT
TALRPositivePositiveHigher than WTSimilar to WT
IIALKNegativeHighly positiveSimilar to WTSimilar to WT
KDNegativeHighly positiveSimilar to WTSimilar to WT
IIICNRNegativeWeakly positiveHigher than WTSimilar to WT
LLWeakly PositiveWeakly positiveHigher than WTHigher than WT
PAHSNegativeNegativeHigher than WTSimilar to WT
IV172RNegativeWeakly positiveLower than WTLower than WT
182LNegativeWeakly positiveLower than WTLower than WT
VStopNegativeNegativeNegativeNegative