CNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan

Figure 1 Weight changes of the five groups of rats. Data are presented as mean ± SE. N: Primary control group; M: Depression model group; D; Low dose Xiaoyaosan (XYS) group; Z: Middle dose XYS group; G: High dose XYS group. On the 21^st day, the difference between the depression model group and the primary control group was significant (n = 9; ^bP < 0.01 vs M). The difference between the XYS groups and the depression model group was significant (n = 9; ^bP < 0.01 vs M).