Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index

Table 2 Subgroup and meta-regression analyses of waist circumference and the risk of nonalcoholic fatty liver disease

Covariates	Subgroup	Studies, n	OR(95%CI)	P of Q	I2	Inter-groupP value	UnivariateP value	MultivariateP value
Per-unit increase in waist circumference
Region	East	9	1.076 (1.025-1.129)	0.000	73.6	0.006	0.171	0.214
	West	2	1.031 (1.016-1.046)	0.535	0.0
Design	c-s	8	1.063 (1.014-1.114)	0.000	79.1	0.157	0.764	0.984
	Others	3	1.071 (1.026-1.119)	0.254	26.9
Adjusted	Yes	7	1.051 (1.019-1.084)	0.035	55.8	0.031	0.489	0.770
(> 3 confounders)	No	4	1.126 (1.000-1.269)	0.000	85.0
Individuals	Yes	6	1.054 (1.025-1.083)	0.055	56.7	0.163	0.728	0.975
(> 700)	No	5	1.100 (0.991-1.22)	0.000	81.5
High vs low category of waist circumference
Design	c-s	5	2.113 (1.615-2.765)	0.180	36.2	0.057	0.642	0.947
	Others	2	4.072 (2.189-7.575)	0.512	0.0
Individuals	Yes	3	2.070 (1.546-2.774)	0.245	28.9	0.122	0.635	0.942
(> 600)	No	4	3.185 (2.010-5.046)	0.164	41.2