Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality

Table 5 Adjusted Cox regression analyses of components of fatty liver index for prediction of type-2 diabetes, incident coronary heart disease and mortality, by gender

	Total		Men		Women
	HR	95%CI	HR	95%CI	HR	95%CI
Diabetes
Waist circumference, 12 cm	1.70	1.33; 2.15	1.64	1.13; 2.38	1.78	1.27; 2.46
Body mass index, 5 kg/m2	1.10	0.91; 1.33	1.06	0.80; 1.40	1.11	0.86; 1.44
Triglycerides, 90 mg/dL	1.22	1.06; 1.40	1.09	0.91; 1.31	1.43	1.20; 1.71
γ-glutamyltransferase, 1.7-fold	2.19	1.61; 2.99	2.44	1.52; 3.92	2.22	1.44; 3.43
CHD
Waist circumference, 12 cm	1.21	0.80; 1.82	1.21	0.20; 1.82	1.02	0.78; 1.33
Body mass index, 5 kg/m2	1.01	0.84; 1.20	0.77	0.52; 1.14	0.98	0.80; 1.20
Triglycerides, 90 mg/dL	1.19	1.03; 1.35	1.20	1.01; 1.43	1.12	0.84; 1.31
γ-glutamyltransferase, 1.7-fold	1.52	0.94; 2.44	1.52	0.94; 2.44	1.64	1.16; 2.31
Mortality
Waist circumference, 12 cm	1.31	1.00; 1.74	1.21	0.81; 1.80	1.38	0.90; 2.11
Body mass index, 5 kg/m2	0.73	0.56; 0.96	0.68	0.45; 1.03	0.82	0.56; 1.20
Triglycerides, 90 mg/dL	1.12	0.96; 1.31	1.28	1.01; 1.57	0.91	0.70; 1.20
γ-glutamyltransferase, 1.7-fold	1.37	0.97; 1.93	1.28	0.79; 2.06	1.62	0.95; 2.77

Models were adjusted also to sex, age, smoking status, systolic BP, HDL-cholesterol. Further, uric acid protected men against diabetes and weakly tended to protect women against CHD.