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©The Author(s) 2015.
World J Gastroenterol. Dec 28, 2015; 21(48): 13555-13565
Published online Dec 28, 2015. doi: 10.3748/wjg.v21.i48.13555
Published online Dec 28, 2015. doi: 10.3748/wjg.v21.i48.13555
Table 3 Adjusted Cox regression analyses of fatty liver disease for prediction of type-2 diabetes and incident coronary heart disease, by gender (and diabetic status)
Total | Men | Women | ||||
HR | 95%CI | HR | 95%CI | HR | 95%CI | |
Diabetes n = | 203/14901 | 110/7071 | 93/7831 | |||
Gender, female | 0.82 | 0.56; 1.20 | ||||
Age, 11 yr2 | 1.14 | 0.97; 1.34 | 1.13 | 0.90; 1.41 | 1.14 | 0.90; 1.46 |
Current smoking, n = 480 | 1.38 | 0.94; 2.00 | 1.35 | 0.84; 2.16 | 1.39 | 0.74; 2.69 |
Former smoking, n = 183 | 1.32 | 0.83; 2.08 | 1.22 | 0.72; 2.06 | 1.98 | 0.72; 5.48 |
HDL-cholesterol, 12 mg/dL | 0.91 | 0.78; 1.06 | 0.96 | 0.77; 1.21 | 0.89 | 0.71; 1.10 |
Systolic BP, 25 mmHg | 1.16 | 1.00; 1.38 | 1.28 | 1.03; 1.60 | 1.08 | 0.88; 1.35 |
Uric acid, 1.3 mg/dL | 0.87 | 0.76; 0.996 | 0.81 | 0.67; 0.97 | 0.94 | 0.76; 1.15 |
Probable FLD, n = 423 | 1.44 | 0.80; 2.57 | 1.57 | 0.72; 3.43 | 1.28 | 0.52; 3.12 |
FLD, n = 673 | 4.93 | 2.98; 8.14 | 4.80 | 2.40; 9.59 | 5.33 | 2.53; 11.2 |
DM incid. per 1000 person-yr | 16.6 | 18.8 | 14.5 | |||
CHD: Diabetic sample n = | 88/4091 | 45/1921 | 43/2171 | |||
Gender, female | 0.95 | 0.55; 1.63 | ||||
Age, 11 years | 1.18 | 0.94; 1.49 | 1.27 | 0.90; 1.80 | 1.10 | 0.79; 1.56 |
Current smoking | 1.12 | 0.64; 1.95 | 1.46 | 0.68; 3.15 | 0.66 | 0.25; 1.75 |
Former smoking | 1.13 | 0.56; 2.31 | 1.36 | 0.59; 3.13 | 1.12 | 0.15; 8.52 |
Alcohol usage, yes/no | 0.50 | 0.12; 2.10 | 0.58 | 0.14; 2.45 | No user | |
HDL-cholesterol, 12 mg/dL | 0.78 | 0.61; 1.00 | 0.90 | 0.62; 1.28 | 0.69 | 0.48; 0.99 |
Systolic BP, 25 mmHg | 0.95 | 0.72; 1.28 | 0.98 | 0.60; 1.60 | 0.93 | 0.65; 1.31 |
Uric acid, 1.3 mg/dL | 0.98 | 0.79: 1.23 | 0.73 | 0.54: 0.999 | 1.35 | 0.99: 1.84 |
Probable FLD | 1.45 | 0.66; 3.18 | 1.68 | 0.56; 5.05 | 1.32 | 0.42; 4.11 |
FLD | 3.59 | 1.78; 7.23 | 4.61 | 1.72; 12.4 | 3.12 | 1.17; 8.35 |
CHD inciden. per 1000 person-yr | 25.3 | 27.4 | 23.4 | |||
CHD: Whole sample n = | 237/15051 | 104/716 | 133/7891 | |||
Gender, female | 1.34 | 0.96; 1.86 | ||||
Age, 11 yr | 1.48 | 1.27; 1.71 | 1.54 | 1.26; 2.00 | 1.43 | 1.17; 1.73 |
Current smoking | 1.50 | 1.06; 2.13 | 1.80 | 1.12; 2.90 | 1.13 | 0.64; 1.98 |
Former smoking | 1.02 | 0.64; 1.63 | 0.92 | 0.51; 1.64 | 1.82 | 0.79; 4.17 |
Alcohol usage, yes/no | 0.80 | 0.37; 1.74 | 0.79 | 0.36; 1.75 | Too few | |
HDL-cholesterol, 12 mg/dL | 0.90 | 0.78; 1.02 | 1.04 | 0.84; 1.28 | 0.81 | 0.69; 0.98 |
Systolic BP, 25 mmHg | 1.25 | 1.08; 1.42 | 1.31 | 1.12; 1.27 | 1.25 | 1.05; 1.45 |
Presence of diabetes | 1.44 | 0.98; 2.13 | 1.81 | 1.04; 3.17 | 1.13 | 0.65; 1.95 |
Probable FLD | 1.26 | 0.83; 1.92 | 1.79 | 0.92; 3.47 | 0.99 | 0.57; 1.73 |
FLD | 1.72 | 1.17; 2.53 | 2.35 | 1.25; 4.43 | 1.42 | 0.86; 2.35 |
CHD incid. per 1000 person-yr | 18.9 | 17.5 | 19.7 |
- Citation: Onat A, Can G, Kaya A, Akbaş T, Özpamuk-Karadeniz F, Şimşek B, Çakır H, Yüksel H. Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality. World J Gastroenterol 2015; 21(48): 13555-13565
- URL: https://www.wjgnet.com/1007-9327/full/v21/i48/13555.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i48.13555