Use of a clinical pathway in laparoscopic gastrectomy for gastric cancer

Table 8 Clinical factors that affect dropout n (%)

	Total	Drop	Univariate		Multivariable1
			OR (95%CI)	P value	OR (95%CI)	P value
Sex				< 0.001		< 0.001
Male	2920	534 (18.29)	1.622 (1.372-1.917)		1.459 (1.228 -1.734)
Female	1880	228 (12.13)	1		1
Age (yr)
≤ 65	3562	462 (12.97)	1		1
> 65	1238	300 (24.23)	2.146 (1.824 -2.525)	< 0.001	1.727 (1.448-2.059)	< 0.001
BMI (kg/m2)
≤ 25	3325	496 (14.92)	1
> 25	1475	266 (18.03)	1.255 (1.066-1.478)	0.006
Anastomosis method
Intra	2345	378 (16.12)	1		1
Extra	2455	384 (15.64)	0.965 (0.826-1.126)	0.651	1.057 (0.900-1.242)	0.499
Resection
Distal	4218	593 (14.06)	1		1
Total	582	169 (29.04)	2.501 (2.050-3.052)	< 0.001	2.444 (1.988-3.005)	< 0.001
Resection group
I-distal	2018	285 (14.12)	1	< 0.001
I-total	327	93 (28.44)	2.417 (1.843 -3.169)	< 0.001
E-distal	2200	308 (14.00)	0.990 (0.832 -1.178)	0.909
E-total	255	76 (29.80)	2.582 (1.920-3.472)	< 0.001
Combined OP
None	4531	694 (15.32)	1		1
Yes	269	68 (25.28)	1.870 (1.404-2.491)	< 0.001	1.731 (1.284-2.334)	< 0.001
OP event
None	4723	732 (15.50)	1		1
Yes	77	30 (38.96)	3.480 (2.187-5.539)	< 0.001	2.558 (1.554-4.212)	< 0.001
Number of comorbidities
0	3196	411 (12.86)	1	< 0.001	1	0.031
1	1137	221 (19.44)	1.635 (1.366 -1.957)	< 0.001	1.179 (0.882 -1.576)	0.266
2 and more	467	130 (27.84)	2.614 (2.082-3.281)	< 0.001	1.564 (1.110-2.204)	0.011
ASA score
1	3025	382 (12.63)	1	< 0.001	1	0.006
2	1549	305 (19.69)	1.696 (1.438-2.000)	< 0.001	1.182 (0.893-1.565)	0.242
3	226	75 (33.19)	3.437 (2.554-4.625)	< 0.001	1.889 (1.271-2.808)	0.002
Abdominal OP history
None	4057	661 (16.29)	1
Yes	743	101 (13.59)	0.808 (0.645-1.013)	0.065
TNM stage
I	4380	688 (15.71)	1	0.274
II	314	51 (16.24)	1.041 (0.763-1.420)	0.802
III	106	23 (21.70)	1.487 (0.930-2.377)	0.097

¹Backward elimination. Logistic regression to predict dropout (= 762/4800). OR: Odd ratio; BMI: Body mass index; Intra/I: Intracorporeal anastomosis; Extra/E: Extracorporeal anastomosis; OP: Operation; ASA: American Society of Anesthesiologists.